Let’s talk about retatrutide, the new medication being studied for weight loss.
So far the human trials suggest a powerful effect with weight loss of 24-27%, along with reductions in liver fat. In this video I look at just how retatrutide works. Next week I’ll discuss what we can do about minimizing the risks which include muscle loss, increased heart rate, and effects on mood.
References: Giblin K, Kaplan LM, Somers VK, Le Roux CW, Hunter DJ, Wu Q, Lalonde A, Ahmad N, Bethel MA. Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials. Diabetes Obes Metab. 2026 Jan;28(1):83-93. doi: 10.1111/dom.70209. Epub 2025 Oct 15. PMID: 41090431; PMCID: PMC12673447.
